Welcome to the Fetcho lab!
Our lab studies how movements are produced by the brain and spinal cord of vertebrates. We use zebrafish as a model system because they allow us to combine genetic and optical methods with more conventional physiological approaches to study the neural circuits. In addition to studies of normal function, we examine disruptions of function by genetic mutations, and are developing approaches to cure spinal injuries.
Most of our work focuses on the larval zebrafish, which are small (4millimeters long) and transparent,
in contrast to the larger, striped, and opaque adults.
Our work uses a combination of behavioral studies, morphological studies of fluorescently labeled neurons in living fish, imaging of neuronal activity in live animals, and electrophysiological studies.